Alzheimer’s Causes Poor Blood Flow To The Brain And Affects Cognitive Function

Alzheimer’s causes poor blood flow to the brain and affects cognitive function, according to a new study conducted on mouse models. People living with Alzheimer’s disease experience reduction in blood flow to the brain and the condition affect cognitive function. Now a new research has revealed the actual reason behind this poor blood flow.

In a new study, researchers focused on understanding how and why, in this type of dementia, the poor vascular function can contribute to cognitive decline. A previous study published in Alzheimer’s and Dementia, the journal of the Alzheimer’s Association marks vascular dysfunction as the disregarded partner of Alzheimer’s disease.

Now, a researchers’ team from Cornell University in Ithaca, NY identified that weak blood flow to the brain can cause cognitive decline. These findings now feature in the journal Nature Neuroscience.

The team explains that white blood cells penetrate inside brain capillaries, which holds oxygenated blood to this organ. In such a case, blood flow to the brain decreases considerably.

“What we’ve done is identify the cellular mechanism that causes reduced brain blood flow in Alzheimer’s disease models, which is neutrophils white blood cells sticking in capillaries,” notes study author Chris Schaffer.

“We’ve shown that when we block the cellular mechanism that causes the clogging, we get improved blood flow, and associated with that improved blood flow is the immediate restoration of cognitive performance of spatial- and working memory tasks.”

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